Aprovel 300 mg

Irbesartan 300 mg

Dosing & Uses
Adult

Dosage Forms & Strengths

tablet

  • 75 mg
  • 150 mg
  • 300 mg

Hypertension

150 mg/day PO initially; may be increased to 300 mg/day PO

Hypovolemia: 75 mg/day PO initially

Nephropathy in Type 2 Diabetes

75-300 mg/day PO

Dosage Modifications

Mild-to-severe renal impairment: Dosage adjustment not necessary unless patient is hypovolemic

Dosing Considerations

Also given in combination with hydrochlorothiazide (Avalide)

Generally, adjust dosage monthly; adjust more aggressively in high-risk patients

Focal Segmental Glomerulosclerosis (Orphan)

Irbesartan and propagermanium: Orphan designation for treatment of focal segmental glomerulosclerosis

Sponsor

  • Dimerix Bioscience Ltd; Level 2, 25 Flinders Lane; Melbourne

Pediatric

Dosage Forms & Strengths
tablet

  • 75 mg
  • 150 mg
  • 300 mg
Hypertension
<6 years: Safety and efficacy not established
6-12 years: 75 mg/day PO initially; not to exceed 150 mg/day
>12 years: 150 mg/day PO initially; may be increased to 300 mg/day PO

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Aprovel 300 mg only for the indication prescribed.