Diarol 1mg

Repaglinide 1mg

Warnings
Contraindications
Hypersensitivity to repaglinide
Diabetic ketoacidosis
Type I diabetes mellitus
Coadministration of gemfibrozil results in increased repaglinide plasma concentration (8-fold increase); may lead to severe hypoglycemia

Cautions
Stress due to infection, fever, trauma, or surgery; may need to discontinue if exposed to stress
Hepatic/renal insufficiency
Patients at risk of severe hypoglycemia: Elderly, debilitated, or malnourished; adrenal or pituitary insufficiency
Myocardial ischemia reported in patients treated concomitantly with NPH-insulin; not indicated for use in combination with NPH-insulin
Use caution in elderly and malnourished patients
Pregnancy or lactation
The use of sulfonylureas may be associated with increased cardiovascular events
Drugs that inhibit organic anion transporting protein OATP1B1 (eg, cyclosporine) may increase plasma concentrations of repaglinide, which is a substrate for active hepatic uptake transporter OATP1B1

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Diarol 1mg only for the indication prescribed.