Inflacam 20mg /1ml

Piroxicam 20mg


Half-life:14-158 hr (average 50 hr)

Onset: 15-30 min (single 20 mg dose); 1 hr (multiple 20 mg doses)

Duration: 48-72 hr

Peak Plasma

Time: 3-5 hr (a single 20 mg dose)

Concentration: 1.5-2 mcg/mL (single 20 mg dose); 3-8 mcg/mL (multiple-dose of 20 mg daily)

Other Information

Protein Bound: 99.3% (with plasma concentrations 5-30 mcg/mL)

Vd: 0.12-0.14 L/kg

Metabolism: hydroxylation at the 5 position of the pyridyl side chain; conjugation by cyclodehydration, hydrolysis of: amide linkage, decarboxylation, ring contraction, N-demethylation

Metabolites: hydroxy, parent drug

Excretion: urine, feces

Enzymes inhibited: cyclooxygenase

Mechanism of Action

Inhibits synthesis of prostaglandins in body tissues by inhibiting cyclooxygenase; at least 2 isoenzymes, cyclooxygenase-1 (COX-1) & -2 (COX-2)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Inflacam 20mg /1ml only for the indication prescribed.

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