Naloxone Mylan 0.4mg /1ml

Naloxone 0.4mg

Warnings

Contraindications

Hypersensitivity

Cautions

Caution in patients with cardiovascular disease or patients receiving medications with potential adverse cardiovascular effects

Caution in patients with history of seizures; avoid use in treatment of meperidine-induced seizures

Recurrence of respiratory depression may occur if opioid involved is long-acting or a partial agonist (eg, methadone, buprenorphine); observe patients until there is no further risk of recurrent respiratory or CNS depression

Avoid excessive dosages after use of opioids in surgery; abrupt postoperative reversal may unmask pain and may cause nausea, vomiting, sweating, seizures, hypertension, and tachycardia; other cardiovascular events, including pulmonary edema and arrhythmias may occur

Auto-injector (Evzio)

  • Monitor injection site for residual needle parts and signs of infection when used to administered to infants <1year of age

Opioid withdrawal

  • Use in patients who are opioid dependent may precipitate acute abstinence syndrome
  • Syndrome characterized by body aches, diarrhea, tachycardia, fever, runny nose, sneezing, piloerection, sweating, yawning, nausea or vomiting, nervousness, restlessness, or irritability, shivering or trembling, abdominal cramps, weakness, and hypertension
  • In neonates, opioid withdrawal may be life-threatening if not recognized and properly treated and may include convulsions, excessive crying, and hyperactive reflexes

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Naloxone Mylan 0.4mg /1ml only for the indication prescribed.