Optipred 1%

Prednisolone 10 mg

Warnings
Contraindications
Documented hypersensitivity
Systemic fungal infection, varicella, superficial herpes simplex keratitis
Receipt of live or attenuated live vaccine; Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) state that administration of live virus vaccines usually is not contraindicated in patients receiving corticosteroid therapy as short-term (<2 weeks) treatment, in low-to-moderate dosages, as long-term alternate-day treatment with short-acting preparations, or in maintenance of physiologic dosages (replacement therapy)

Cautions
Use with caution in cirrhosis, diabetes, ocular herpes simplex, hypertension, diverticulitis, following myocardial infarction, thyroid disease, seizure disorders, hypothyroidism, myasthenia gravis, hepatic impairment, peptic ulcer disease, osteoporosis, ulcerative colitis, psychotic tendencies, untreated systemic infections, renal insufficiency, pregnancy
Thromboembolic disorders or myopathy may occur
Delayed wound healing is possible
Patients receiving corticosteroids should avoid chickenpox or measles-infected persons if unvaccinated
Latent tuberculosis may be reactivated (patients with positive tuberculin test should be monitored)
Some suggestion (not fully substantiated) of slightly increased cleft palate risk if corticosteroids are used in pregnancy
Parenteral forms (prednisolone sodium phosphate) have been discontinued
Suppression of hypothalamic-pituitary-adrenal axis may occur particularly in patients receiving high doses for prolonged periods or in young children; discontinuation of therapy should be done through slow taper
Posterior subcapular cataract formation associated with prolonged use of corticosteroids
Prolonged use of corticosteroids may increase risk of secondary infections
Increase in intraocular pressure associated with prolonged use of corticosteroids
Long-term use associated with fluid retention and hypertension
Development of Kaposi's sarcoma associated with prolonged corticosteroid use
Acute myopathy associated with high dose of corticosteroids
Corticosteroid use may cause psychiatric disturbances
If product is used for 10 days or longer, intraocular pressure should be routinely monitored even though it may be difficult in children and uncooperative patients; steroids should be used with caution in the presence of glaucoma. Intraocular pressure should be checked frequently
Steroids after cataract surgery may delay healing and increase incidence of bleb formation
Use of ocular steroids may prolong course and may exacerbate severity of many viral infections of the eye (including herpes simplex)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Optipred 1% only for the indication prescribed.