Cloracef mr 500mg

Cefaclor 500mg

Pharmacology
Mechanism of Action
Second-generation cephalosporin that binds to one or more of the penicillin-binding proteins, which in turn inhibits cell wall synthesis and results in bactericidal activity. Has gram-positive activity that first-generation cephalosporins have and adds activity against Proteus mirabilis, H influenzae, Escherichia coli, Klebsiella pneumoniae, and Moraxella catarrhalis. Indicated for management of infections caused by susceptible mixed aerobic-anaerobic microorganisms. Determine proper dosage and route based on condition of patient, severity of infection, and susceptibility of causative organism

Pharmacokinetics
Half-Life: 0.5-1 hr, prolonged with renal impairment
Peak Plasma Time: capsule 60 min, suspension 45 min
Protein Bound: 25%
Absorption: well absorbed, acid stable
Distribution: crosses placenta
Metabolism: Partial, hepatic
Excretion: Unchanged in urine: 80%

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Cloracef mr 500mg only for the indication prescribed.