Azomycin 200mg/5ml

Azithromycin 200mg

Mechanism of Action
Binds to 50S ribosomal subunit of susceptible microorganisms and blocks dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest; does not affect nucleic acid synthesis
Concentrates in phagocytes and fibroblasts, as demonstrated by in vitro incubation techniques; in vivo studies suggest that concentration in phagocytes may contribute to drug distribution to inflamed tissues

Rapidly absorbed
Bioavailability: 37%; variable effect with food (increased with oral suspension, unchanged with tablet)
Peak serum time: 2-3 hr (immediate release); 5 hr (extended release)

Extensively distributed into skin, lungs, sputum, tonsils, and cervix; penetrates cerebrospinal fluid (CSF) poorly
Protein bound: 7-50% (concentration dependent)
Vd: 33.3 L/kg (PO); 31.1 L/kg (IV)

Metabolized in liver

Half-life: ~70 hr (immediate release); 59 hr (extended release)
Excretion: Feces (50% as unchanged drug), urine (5-12%)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Azomycin 200mg/5ml only for the indication prescribed.