Naloxone Mylan 0.4mg /1ml

Naloxone 0.4mg


IV Compatibilities

Additive: Verapamil

Syringe: Heparin, ondansetron, dimehydrinate

Y-site: Fenoldopam, gatifloxacin, linezolid, propofol

IV Incompatibilities

Syringe: Pantoprazole

Y-site: Amphotericin B cholSO4

IV Preparation

For infusion, dilute to 4 mcg/mL in D5W or NS

Use within 24 hr

IM/SC Preparation

Before using, check to make sure the solution is not discolored

Replace if the solution is discolored or contains a precipitate

IM/SC Administration

For IM or SC use only

Seek emergency medical care immediately after use

Since the duration of action of most opioids exceeds that of naloxone and the suspected opioid overdose may occur outside of supervised medical settings, seek immediate emergency medical assistance, keep the patient under continued surveillance until emergency personnel arrive, and administer repeated naloxone doses as necessary


  • Administer in anterolateral aspect of the thigh in adult and pediatric patients
  • Upon actuation, the autoinjector automatically inserts the needle IM or SC, and thereby delivers the naloxone injection, and then retracts the needle fully into its housing
  • In pediatric patients aged <1 yr, the caregiver should pinch the thigh muscle while administering the dose
  • Administer additional doses using a new auto-injector, if the patient does not respond or responds and then relapses into respiratory depression
  • Additional doses may be given q2-3min until emergency medical assistance arrive


Store at controlled room temperature 15-25°C (59-77°F) excursions permitted between 4-40°C (39-104°F)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Naloxone Mylan 0.4mg /1ml only for the indication prescribed.