Optipred 1%

Prednisolone 10 mg

Mechanism of Action
Glucocorticosteroid; elicits mild mineralocorticoid activity and moderate anti-inflammatory effects; controls or prevents inflammation by controlling rate of protein synthesis, suppressing migration of polymorphonuclear leukocytes (PMNs) and fibroblasts, reversing capillary permeability, and stabilizing lysosomes at cellular level

Duration: 18-36 hr
Peak plasma time: 5 min (IV); 1 hr (PO)

Protein bound: 65-91% (lower in elderly)
Vd: 0.22-0.7 L/kg

Extensively metabolized in liver

Half-life: 3.6 hr (normal renal function); 3-5 hr (end-stage renal disease)
Dialyzable: Hemodialysis, no
Renal clearance: 9.5 mL/min
Excretion: Urine (mainly)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Optipred 1% only for the indication prescribed.