Ins. humulin n 100i.u/ml 1v 10ml

Insulin isophane 100 i.u.

Pharmacology
Mechanism of Action
Regulates glucose metabolism
Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production; insulin inhibits lipolysis and proteolysis, and enhances protein synthesis
Insulin NPH and insulin regular is a combination insulin product with intermediate duration that has more rapid onset than that of insulin NPH alone

Pharmacokinetics
Onset: 1-1.5 hr (NPH); 0.5 hr (regular)
Peak: 4-12 hr (NPH); 2.5-5 hr (regular)
Duration: Up to 24 hr (NPH); 8 hr (regular)
Bioavailability: IM, SC, IP: well absorbed
Protein Bound: 5% (not bound to serum binding-protein, but present as a monomer in plasma)
Vd: 0.15 L/kg
Metabolism: Liver >50%; kidney 30%; adipose tissue/muscle 20%

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ins. humulin n 100i.u/ml 1v 10ml only for the indication prescribed.

Verified References
  • FDA Feb 10, 2018
  • CDC Feb 10, 2018
  • Mayo Clinic Feb 10, 2018
  • Drugs.com accessed Feb 10, 2018
  • Medscape accessed Feb 10, 2018
  • Epocrates accessed Feb 10, 2018
  • Webmd accessed Feb 10, 2018