Marcofen 300 mg

Ibuprofen 300 mg.

Dosing & Uses

Adult

Dosage Forms & Strengths

tablet

  • 100mg
  • 200mg
  • 400mg (Rx)
  • 600mg (Rx)
  • 800mg (Rx)

capsule

  • 200mg

tablet, chewable

  • 50mg
  • 100mg

oral suspension

  • 100mg/5mL
  • 40mg/mL

Pain/Fever/Dysmenorrhea

OTC: 200-400 mg PO q4-6hr; not to exceed 1.2 g unless directed by physician

Prescription: 400-800 mg PO/IV q6hr

Inflammatory Disease

400-800 mg PO q6-8hr; not to exceed 3.2 g/day

Osteoarthritis

300 mg, 400 mg, 600 mg, or 800 mg PO q6-8hr; not to exceed 3.2 g/day

Monitor for gastrointestinal (GI) risks

Rheumatoid Arthritis

300 mg, 400 mg, 600 mg, or 800 mg PO q6-8hr; not to exceed 3200 mg/day

Monitor for GI risks

Dosage Modifications

Significantly impaired renal function: Monitor closely; consider reduced dosage if warranted

Severe hepatic impairment: Avoid use

Pediatric

Dosage Forms & Strengths

tablet

  • 100mg
  • 200mg
  • 400mg (Rx)
  • 600mg (Rx)
  • 800mg (Rx)

capsule

  • 200mg

tablet, chewable

  • 50mg
  • 100mg

oral suspension

  • 100mg/5mL
  • 40mg/mL

Fever

6 months to 12 years

5-10 mg/kg/dose PO q6-8hr; not to exceed 40 mg/kg/day

Pain

4-10 mg/kg/dose PO q6-8hr; not to exceed 40 mg/kg/day

Juvenile Idiopathic Arthritis

30-50 mg/kg/24hr PO divided q8hr; not to exceed 2.4 g/day

Patent Ductus Arteriosus

See ibuprofen IV drug monograph

Cystic Fibrosis (Off-label)

<4 years: Safety and efficacy not established

≥4 years: PO administration q12hr, adjusted to maintain serum levels of 50-100 mcg/mL; may slow disease progression in younger patients with mild lung disease

Dosing Considerations

Potential toxic dose in children <6 years: 200 mg/kg

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Marcofen 300 mg only for the indication prescribed.

Verified References
  • FDA Dec 17, 2017
  • CDC Dec 17, 2017
  • Mayo Clinic Dec 17, 2017
  • Drugs.com accessed Dec 17, 2017
  • Medscape accessed Dec 17, 2017
  • Epocrates accessed Dec 17, 2017
  • Webmd accessed Dec 17, 2017