Omez 10

Omeprazole 10 mg.

Dosing & Uses
Adult

Dosage Forms & Strengths

packet

  • 2.5 mg
  • 10 mg

suspension

  • 2 mg/mL

tablet, delayed release

  • 20 mg

capsule, delayed release

  • 10 mg
  • 20 mg
  • 40 mg

Duodenal Ulcer

20 mg PO qDay for 4-8 weeks

Safety and efficacy of omeprazole for maintenance treatment past 1 year not established

Helicobacter Pylori Infection

Various regimens exist of PPIs combined with antibiotics, 1 example is listed below

20 mg PO q12hr for 10 days, WITH

Amoxicillin 1000 mg PO q12hr, AND

Clarithromycin 500 mg PO q12hr for 10-14 days

Dosing considerations

  • This regimen is available as a prepackaged 10-day supply of omeprazole, amoxicillin, and clarithromycin from Dava Pharms Inc, for eradication of H pylori

Gastric Ulcer

40 mg PO qDay for 4-8 weeks

GERD

20 mg PO qDay for 4 weeks

Erosive Esophagitis

20 mg PO qDay for 4-8 weeks

Maintenance: 20 mg PO qDay for up to 1 year

Hypersecretory Condition (eg,  Zollinger-Ellison Syndrome)

60 mg PO qDay (initial) up to 360 mg/day divided q8hr PO  

If dose >80 mg, divide it

Dosage Modifications

Hepatic impairment: Not studied; expert analysis recommends a reduction in dose, especially for maintenance of healing of erosive esophagitis

Renal impairment: Dose adjustments not necessary

Pediatric

Dosage Forms & Strengths
packet

  • 2.5 mg
  • 10 mg
suspension

  • 2 mg/mL
tablet/capsule

  • 10 mg
  • 20 mg
  • 40 mg
GERD
Indicated for treatment of GERD
<1 year: Safety and efficacy not established
5-10 kg: 5 mg PO qDay
10-20 kg: 10 mg PO qDay
>20 kg: 20 mg PO qDay

Erosive Esophagitis
Indicated for treatment and to maintain healing of erosive esophagitis caused by acid-mediated GERD
Treatment

  • <1 month: Safety and efficacy not established
  • Aged 1 month to <1 year
  1. 3 to <5 kg: 2.5 mg qDay
  2. 5 to <10 kg: 5 mg qDay
  3. ≥10 kg: 10 mg qDay
  4. May treat for up to 6 weeks
  • Aged 1-16 years
  1. 5 to <10 kg: 5 mg PO qDay
  2. 10 to <20 kg: 10 mg PO qDay
  3. ≥20 kg: 20 mg PO qDay
  4. May treat for 4-8 weeks
Maintenance of healing

  • <1 year: Safety and efficacy not established
  • ≥1 year: Controlled trials for maintenance do not extend beyond 12 months
Neonates (Off-label)
Refractory duodenal ulcer or reflux esophagitis: 0.5-1.5 mg/kg PO qDay for up to 8 weeks 

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Omez 10 only for the indication prescribed.